Last year's runner-up Ferrer of Spain, the fifth seed, bulldozed his way into the last 32 by demolishing Italian Bolelli in 108 minutes.
The fifth seed, who could take on eight-times champion Rafa Nadal in the quarter-finals, will next play Argentine Juan Monaco or Italian 32nd seed Andreas Seppi.
"I am ready for the next round and was very happy with my performance, especially with my consistency," he said.
"My season on clay has been good (when asked about beating Nadal on clay this season). I have a good feel but I'm focusing on the moment."
